Anti-Sclerostin抗體,骨形態(tài)發(fā)生抑制蛋白SOST

英文介紹：Negative regulator of bone growth.Sclerostin (SOST) is a bone morphogenetic protein (BMP) antagonist, leading to the activation of BMP signaling. It negatively regulates the formation of bone by repressing the differentiation and/or function of osteoblasts induced by BMPs. It has been shown that Sclerostin binds BMP-5, -6, and -7 with high affinity and BMP-2 and -4 with low affinity. The noggin-sclerostin protein complex represents a novel mechanism for the fine-tuning of BMP activity in bone homeostasis. Evidence is accumulating that one of the important mechanisms of bone regulation by sclerostin is the modulation of Wnt/Beta-catenin signaling. Sclerostin also rapidly activated ERK-1/2 MAPK signaling, indicating the involvement of additional signaling pathways.
此產(chǎn)品本公司有標(biāo)記的一抗出售，相關(guān)標(biāo)記有：Alexa Fluor 350 標(biāo)記、Alexa Fluor 488 標(biāo)記、Alexa Fluor 555 標(biāo)記、Alexa Fluor 647 標(biāo)記、AP標(biāo)記、APC標(biāo)記、Biotin標(biāo)記、Cy3標(biāo)記、Cy5標(biāo)記、Cy5.5標(biāo)記、Cy7標(biāo)記、FITC標(biāo)記、Gold標(biāo)記、HRP標(biāo)記、PE標(biāo)記、PE-Cy3標(biāo)記、PE-CY5標(biāo)記、PE-CY5.5標(biāo)記、PE-CY7標(biāo)記、RBITC標(biāo)記
注意事項(xiàng):This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品名稱：Anti-Sclerostin抗體,骨形態(tài)發(fā)生抑制蛋白SOST

產(chǎn)品編號(hào)：BYK-6194R
英文名稱：Anti-Sclerostin
中文名稱：骨形態(tài)發(fā)生抑制蛋白SOST抗體
英文別名：BEER; Cortical hyperostosis with syndactyly; Sclerosteosis; Sclerostin; SOST; SOST_HUMAN; VBCH.
產(chǎn)品規(guī)格：0.1ml/0.2ml
此抗體本公司有單抗和多抗，可用于免疫組化（IHC），免疫印跡（WB），酶聯(lián)免疫(ELISA)，IF、IP、流式細(xì)胞術(shù)等實(shí)驗(yàn)（可來(lái)電索取說(shuō)明）
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Anti-Sclerostin抗體,骨形態(tài)發(fā)生抑制蛋白SOST產(chǎn)品現(xiàn)貨銷售，其他同類產(chǎn)品：

byk-1381R    *抑制蛋白激酶C底物抗體    Anti-AKAP12/Gravin
byk-11381R    A2LD1蛋白抗體    Anti-A2LD1/GGACT
byk-0276R    干燥癥SSB/La抗體    Anti-SSB/La
byk-10276R    磷脂酰肌醇激酶PIK3-γ抗體    Anti-PIK3 gamma
byk-0635R    核糖核蛋白抗原抗體    Anti-SSA/RO52
byk-1899R    凋亡基因抗體    Anti-SRG11/Spata17
byk-11899R    核因子1B抗體    Anti-NFIB/NF1B2
byk-1898R    特異表達(dá)新基因5抗體    Anti-SRG5/SPATA12
byk-11898R    核因子1A抗體    Anti-NFIA/NF-1
byk-1897R    突觸結(jié)合蛋白4抗體    Anti-Synaptotagmin-4
byk-11897R    環(huán)指蛋白67抗體    Anti-NEURL/RNF67
byk-1136R    突觸結(jié)合蛋白相關(guān)基因2抗體    Anti-synaptotagmin-2
byk-11136R    原鈣粘蛋白β2抗體    Anti-PCDHB2
byk-2536R    *調(diào)節(jié)元件結(jié)合蛋白2抗體    Anti-SREBP-2
byk-12536R    磷酸化活化復(fù)制因子2抗體    Anti-phospho-ATF2 (Ser480)
byk-1402R    *調(diào)節(jié)元件結(jié)合蛋白1抗體    Anti-SREBP-1
byk-11402R    20號(hào)染色體開(kāi)放閱讀框100抗體    Anti-GCX1/C20orf100
byk-1401R    血清應(yīng)答因子抗體    Anti-SRF
byk-11401R    醛固酮還原酶家族1成員C3抗體    Anti-AKR1C3/DD3
byk-1730R    磷酸化Src原癌基因抗體    Anti-phospho-Src(Tyr529)
byk-11730R    鉀通道蛋白1抗體    Anti-Kv1.1
byk-1135R    src原癌基因抗體    Anti-SRC
byk-11135R    原鈣粘蛋白16抗體    Anti-PCDHB16
byk-1518R    PSP抗體    Anti-Persephin
byk-11518R    叉頭蛋白D3抗體    Anti-FOXD3
byk-0724R    巢癌相關(guān)蛋白抗體    Anti-Spindlin 1
byk-2653R    鞘氨醇激酶2抗體    Anti-SPHK2
byk-2652R    鞘氨醇激酶1抗體    Anti-SPHK1
byk-2675R    a-包襯蛋白抗體    Anti-SPECA
byk-0381R    血影蛋白A鏈非紅細(xì)胞型/收縮蛋白/Spectrin α抗體    Anti-Spectrin alpha chain, non-erythrocytic 1
byk-10381R    磷酸化細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)分子Smad-1抗體    Anti-Phospho-Smad1 (Ser463)

Anti-Sclerostin抗體,骨形態(tài)發(fā)生抑制蛋白SOST封閉(Blocking):

轉(zhuǎn)膜完畢后，立即把蛋白膜放置到預(yù)先準(zhǔn)備好的Western洗滌液中，漂洗1-2分鐘，以洗去膜上的轉(zhuǎn)膜液。從轉(zhuǎn)膜完畢后所有的步驟，一定要注意膜的保濕，避免膜的干燥，否則極易產(chǎn)生較高的背景。
用微型臺(tái)式真空泵吸盡洗滌液，加入Western封閉液，在搖床上緩慢搖動(dòng),室溫封閉60分鐘。對(duì)于一些背景較高的抗體，可以在4℃ 封閉過(guò)夜。

咨詢及訂購(gòu)的方法：
1.可來(lái)電向我們直接咨詢及訂購(gòu)。：021-6034 0820,158 0061 4926
2.可加客服或交談，向我司在線人員咨詢及訂購(gòu)。
3.可通過(guò)郵件咨詢及訂購(gòu)。