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當(dāng)前位置：世聯(lián)博研（北京）科技有限公司>> SynTumor 3D 腫瘤模型芯片
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更新時間：2023-07-27 18:55:52瀏覽次數(shù)：86次
聯(lián)系我時，請告知來自 環(huán)保在線SynTumor 3D??????C????????????
SynTumor?????3D??????????????????????????????????????????????????????????????????????????á??????????a????????????????????b?????????????????c????????????????????????????/????????????????翪???SynTumor 3D????????????????????????????????????????????
SynTumor 3D Cancer?????????µ?
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?????????о???????????????????????????? SynTumor 3D???????????н??????
????????????????????????????????????????????????????????3D????????
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??2?m??8?m??????
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??2?m??8?m??????
SynTumor 3D?????????????????
??????????????????????SynTumor?????????all????????? ????????о????????????SynTumorо??????????????????????н?????? ????all???????????????????????????????? ???????????????????????????????·?????all???????? ???????????
| SynTumor Kits and Chips | Starter Kit (microvascular) Cat#s 403004, 403008 | Assay Kit (microvascular) Cat#s 403003, 403007 | Starter Kit (idealized) Cat#s 403002, 403006 | Assay Kit (idealized) Cat#s 403001, 403005 |
| 102004-STu (2uM) or 102012-STu (8uM) Chips (10) | ? | ? | ||
| 105007-STu (2uM) or 105015-STu (8uM) Chips (10) | ? | ? | ||
| Pneumatic Primer and Adapter | ? | ? | ||
| Manifold (5 port) | ? | ? | ||
| Blunt Tip Needles 0.5?? long, 24ga (50) | ? | ? | ? | ? |
| Tygon Tubing 0.2?? ID x 0.6?? OD (100 ft) | ? | ? | ? | ? |
| 1 mL Syringes (50) | ? | ? | ? | ? |
| Slide Clamps (25) | ? | ? | ? | ? |
3D culture of endothelial cells and breast cancer cells were evaluated for their viability following treatment with chemotherapeutic drugs. SynTumor model demonstrated significant differences in drug responses under static conditions compared to perfusion and diffusion based modes of interaction commonly observed in vivo.
SynVivo and in vivo response show that both the nanopolymers labeled A and B transfect the core of the tumor with uniform GFP expression following direct injection. In contrast, vascular injection route in SynVivo shows uniform transfection of the tumors only for nanopolymer labeled A matching the observed results in vivo.
Differences between vascular diffusion and perfusion experiments on tumor and endothelial cell viability. Vascular flow and diffusion allows formation of necrotic core similar to in vivo.
Plot of viable cells for the two different modes of drug exposure compared to classical well plate studies. Results from well plate studies over predict the efficacy responses.
SynTumor 3D???C???????
???????????10????м??100??????????25???????У?50????????50??1 ml???????????????????????????????????????SynTumor???????裩??
?????403002??SynTumor 3D?????????????????????2?m???
?????403006??SynTumor 3D??????????????????
?????403004??SynTumor 3D?????????????????????2?m???
?????403008 SynTumor 3D????????????????????????8?m??
SynTumor 3D???C????????
???????????10????м??100??????????25???????У?50????????50??1 ml?????????
?????403001 SynTumor 3D????????У??????????2?m???
?????403005 SynTumor 3D????????У??????????8?m???
?????403003??SynTumor 3D????????У???????????2?m??
?????403007??SynTumor 3D????????У???????????8?m
SynTumor 3D???Cо?
?????102004-STu SynTumor 3D???о????????????100??mOC??100??m??????2??m??????50??m?г??100??m????
?????102012-STu??SynTumor 3D???о????????????200??mOC???????8??m?????50??m?г???C8 /100??m??
?????105007-STu??SynTumor 3D???о????????????2??m????????20??mDia-3??m??????100??m????
?????105015-STu??SynTumor 3D???о????????????8??m????????20??mDia-30??m????100??m????1??????
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